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Co-enzyme Q10 with MCT

Coenzyme Q10, also known as ubiquinone, is a naturally occurring substance and an essential component of the mitochondria - the energy producing unit within our cells. CoQ10 is involved in the production of ATP, the energy molecule. The benefits of CoQ10 centre around energy production and for its benefits as an antioxidant. CoQ10s antioxidant effects reduce lipid peroxidation and assist vitamin E in protecting cell membranes and lipids such as cholesterol from oxidation.

Medium Chain Triglyceride (MCT)

MCTs are derived from coconut oil and consist of a 6 to 12 carbon chain rather than the 18-24 found in polyunsaturated fats (PUFAs). This difference in chain length means that they are metabolised differently. Unlike PUFAs, MCTS do not require pancreatic enzymes and bile acids to be absorbed. Rather than via the lymphatic circulation, MCTs are absorbed directly into the veins and pass through membranes easing their transport, metabolism and bioavailability.


Doses for CoQ10 vary from 30mg up to 400mg depending upon the condition. For general antioxidant protection 30mg is suggested. Clinical effects are noted at higher levels. Results are often noted 8 weeks or more after supplementation as the synthesis of CoQ10-dependent enzymes is a slow process. Up to 85g of MCTs have been used in athletic performance studies, although results have been conflicting.

Potential applications

Cardiovascular disease, fatigue/sports, gastric ulcer, obesity, neuro-muscular degeneration, Parkinson's disease, immune support (e.g. HIV), cancer, HIV infection, diabetes, periodontal disease, infertility.

Known contraindications

Co Q10 is generally well tolerated with no serious adverse effects over long term use. MCTs are generally regarded as safe although diabetics and those with liver disease should avoid high levels of MCTs due to acidosis.


Cholesterol lowering drugs such as statins have been found to lower CoQ10 levels. The beta blockers propranolol and metaprolol also have adverse effects on CoQ10 levels. Tricyclic antidepressants have also been shown to deplete CoQ10-dependent enzymes. Co Q10 at levels of 100mg/day has shown protective effects against the cardio-toxic effects of the anti-cancer drug ADRIAMYCIN. CoQ10 is structurally similar to vitamin K and has been reported to interact with warfarin. Physician's guidance is suggested in those on warfarin medication. No known interactions for MCTs with any drug.

Use in conjunction with

  • Cardiovascular protection - grape seed/pycnogenol, flax seed oil, antioxidant complex, hawthorn berry, folic acid, magnesium with B6 / potassium, vitamin E
  • Fatigue - rhodiola, B-complex, EFAs, high-five multivit., green food blend, balanced iron (if anaemic)
  • Periodontal disease - grape seed / pycnogenol, oregon grape root (topical application around gum), ester C, Echinacea, balanced zinc complex


Severe medical conditions require physician supervision.


© Cheryl Thallon at Viridian

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