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Oregon Grape Root

Berberis aquifolium

Goldenseal is one of the most heavily harvested wild flowers in the USA, as its reputation as an effective natural antibiotic has spread around the world. But its popularity has brought unacceptable pressure upon the plant and experts are now recommending alternatives. Oregon grape's historical and folk use is similar to that of goldenseal. In addition, Oregon grape has been used in the treatment of chronic skin conditions such as acne, psoriasis and eczema. As with goldenseal, the beneficial effects associated with Oregon grape are mainly due to the high levels of isoquinoline alkaloids present, particularly berberine.


250-500mg one to three times daily. Best taken away from food.

Potential applications

Diarrhoea, chronic candidiasis, conjunctivitis/blepharitis, gallstones, skin infections, parasites, poor digestion, psoriasis, urinary tract infections, cellular protection (anti-tumour), trachoma, chronic cholecystitis and liver disorders. Inflammatory states of the mucus membranes, peptic ulcers, colitis, anorexia and painful menstruation.

Known contraindications

Not recommended for use during pregnancy and lactation. Use should be restricted for two to three week periods.


It is suggested that the efficacy of certain drugs i.e. Doxycycline and Tetracycline may be reduced when taken in conjunction with Oregon grape. High doses may interfere with B vitamin metabolism.

Use in conjunction with

Acidophillus, grapefruit seed extract, fibre complex, l-glutamine, digestive aid, green food blend, Echinacea, dandelion/burdock.

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